Protein that may ‘shock and kill’ HIV virus identified

Protein that may ‘shock and kill’ HIV virus identified

  Researchers have identified a protein that can potently force the latent human immunodeficiency virus (HIV) viruses out of hiding and poison them on their way out, leading to potential treatments for the deadly disease. The findings showed that galectin-9 — a human sugar-binding protein — reactivates latent HIV viruses and renders these infected cells visible to the immune system, in a process called the “shock and kill” HIV eradication strategy. Galectin-9 works by manipulating the sugars on the surface of HIV-infected cells to deliver the signals that force latent…

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