Cholesterol deprivation can kill brain tumour cells

Cholesterol deprivation can kill brain tumour cells

Offering new hope for an alternative treatment of brain cancer, researchers have found that depriving the deadly tumour cells of cholesterol, which they import from neighbouring healthy cells, kills tumour cells and causes their regression. “Disrupting cholesterol import by GBM (glioblastoma) cells caused dramatic cancer cell death and shrank tumours significantly, prolonging the survival of the mice,” said senior author Paul Mischel, Professor at University of California San Diego School of Medicine in the US. Glioblastoma (GBM) is the most common and most aggressive form of brain cancer, which is…

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