Tumour hardness may develop cancer cells

Tumour hardness may develop cancer cells

Tumour hardness and hypoxia — lack of oxygen at the tumour’s core — trigger a biological switch that causes cancer stem cells to develop, a recent study has found. This biological switch is critical to a tumour’s ability to invade other tissue — a process called metastasis. “Our study suggests that to combat cancer, we should be developing treatments that target the stiff, hypoxic regions of tumours. We were surprised to see just how important these two properties in the tumour micro-environment — stiffness and hypoxia — were for regulating…

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