Hope for cancer patients: Enzyme linked to colon cancer identified

Hope for cancer patients: Enzyme linked to colon cancer identified

Researchers have identified an enzyme that appears to drive the conversion of normal colon tissue into cancer by attaching sugar molecules, or glycans, to certain proteins in the cell. The research, published in the Journal of Biological Chemistry, showed that the enzyme was absent in healthy colon tissue but abundant in colon cancer cells. “Our data suggest (that) this specific enzyme seems to affect a subset of proteins that could be involved in cell-cell adhesion,” said Hans Wandall from University of Copenhagen in Denmark. In other words, the glycan modifications…

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There’s hope for cancer patients. A jet lag drug could ease chemotherapy-induced pain

There’s hope for cancer patients. A jet lag drug could ease chemotherapy-induced pain

A drug used to ease the effects of jet lag may also prevent the painful side effects of cancer medications, a study claims. Researchers from the University of Edinburgh and University of Aberdeen in the UK found that a drug known as melatonin appeared to prevent pain caused by chemotherapy damage to nerves by blocking the harmful effects on nerve health. They focused on a common condition known as chemotherapy-induced neuropathic pain (CINP), which causes tingling and pain to touch and cold temperatures, that can be severe enough to cause…

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Cow antibodies bring hope for effective AIDS vaccine soon

Cow antibodies bring hope for effective AIDS vaccine soon

In a significant find, a team of researchers has reported for the first time elicitation of powerful, HIV-blocking antibodies in cows in a matter of weeks — a process that usually takes years in humans — paving the way for developing a broadly effective AIDS vaccine in the near future. According to the study, published in the prestigious journal Nature, the unexpected discovery in cows is providing clues for important questions at a moment when new energy has infused HIV vaccine research. “One approach to a preventive HIV vaccine involves…

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Genetically-engineered mosquitoes give hope against dengue

Genetically-engineered mosquitoes give hope against dengue

In a first, researchers have genetically engineered mosquitoes that have an increased resistance to infection by the dengue virus. After decades of research and countless control attempts, dengue continues to infect an estimated 390 million people around the world each year. Now, researchers report that mosquitoes carrying dengue virus (DENV) can be genetically engineered, giving an increased resistance to infection by the virus. When a mosquito bites someone infected with DENV, the virus needs to complete its lifecycle in the mosquito’s gut, eventually infecting its salivary glands, before it can…

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New hope for patients with deadly brain tumour

New hope for patients with deadly brain tumour

Non-invasive gene therapy could treat brain tumour (Fatine El Hassani/Getty Images) Researchers have found a potential new way of stopping one of the most aggressive types of brain tumour from spreading, which could also lead the way to better patient survival. Glioblastoma, which is one of the most common types of malignant brain tumours in adults, grow fast as well as spread easily. The tumour has threadlike tendrils that extend into other parts of the brain making it difficult to remove it all, the study from the University of Southampton…

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