This New Therapy Can Help You Fight Drug Addiction

This New Therapy Can Help You Fight Drug Addiction

Researchers have developed a treatment that may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use. When tested on rats, the new treatment was effective in reducing the animals’ cravings, according to the findings published in the Journal of Medicinal Chemistry. When someone habitually misuses drugs, their brain chemistry is changed in ways that make it harder for them to quit taking drugs despite negative consequences. Once someone has developed this brain disorder, their mind…

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This new drug can reduce post-childbirth bleeding and save lives, says WHO

This new drug can reduce post-childbirth bleeding and save lives, says WHO

Excessive bleeding following childbirth is one of the major causes of death in several countries. Approximately 70,000 women die every year because of post-partum haemorrhage, which also increases the risk of babies dying within a month. “Despite substantial reductions in maternal mortality, hemorrhage continues to be the largest direct cause of maternal death, accounting for 6,61,000 deaths worldwide between 2003 and 2009. More than 70% of hemorrhagic deaths occur post partum, and most are due to uterine atony, which results from poor contraction of the uterus after childbirth,” mentions the…

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Moms-to-be, take note. European experts advise against epilepsy drug in pregnancy

Moms-to-be, take note. European experts advise against epilepsy drug in pregnancy

An expert committee of Europe’s medicines watchdog recommended Friday that a drug used to treat epilepsy and linked to malformations in children not be used in pregnancy. The compound, valproate, is also used for migraine and bipolar disorder, and doctors already advised against prescribing the medicine for pregnant women in France. France’s medicines regulator, known by the acronym ANSM, asked the London-based European Medicines Agency (EMA) to conduct a risk review. The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) said in a statement Friday it was recommending that valproate not be…

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Now, a common asthma drug promises to help delay rare heart complications

Now, a common asthma drug promises to help delay rare heart complications

A common asthma drug has the potential to help delay development of a rare heart complication that lacks effective drug treatment, according to researchers. Aortic aneurysm — the dilation of the aorta — is a serious condition that occurs when the wall of the aorta, the body’s largest artery, weakens and swells. The condition is largely symptom-free and is normally therefore not discovered until late in its development when it threatens to rupture and cause life-threatening haemorrhaging. The findings showed that the asthma drug montelukast blocks leukotrienes — inflammatory signal…

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Brainstorm Health: Antibiotic Resistance, Stem Cell Skin Regeneration, Postpartum Depression Drug

Brainstorm Health: Antibiotic Resistance, Stem Cell Skin Regeneration, Postpartum Depression Drug

That’s where we come in. We mortals help push that fast evolutionary process into warp speed in at least two ways. First, we do it through our long practice of overprescribing and inappropriately prescribing antibiotics to patients. These ineffective treatments often leave in their wake surviving microbes that develop resistance to the drugs used and then pass along those adaptations to subsequent generations. As the saying goes: “Whatever doesn’t kill you, makes you stronger.” (To see how feverishly fast resistant strains can emerge, see this scary timeline.) Secondly, we egg on evolution through another insidious…

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India’s drug prices regulator calls for better oversight of private hospitals

India’s drug prices regulator calls for better oversight of private hospitals

India’s drug pricing authority called for better regulation of the country’s massive private healthcare industry on Friday to ensure government efforts to cut prices benefit patients. To cut the cost of procedures such as angioplasty and knee surgery, India’s National Pharmaceutical Pricing Authority (NPPA) has dramatically reduced prices of knee implants and cardiac stents in recent months. The move has been hailed as a major effort by Indian Prime Minister Narendra Modi to make healthcare affordable, but it has been met with stiff resistance from healthcare providers. Several hospitals across…

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There’s hope for cancer patients. A jet lag drug could ease chemotherapy-induced pain

There’s hope for cancer patients. A jet lag drug could ease chemotherapy-induced pain

A drug used to ease the effects of jet lag may also prevent the painful side effects of cancer medications, a study claims. Researchers from the University of Edinburgh and University of Aberdeen in the UK found that a drug known as melatonin appeared to prevent pain caused by chemotherapy damage to nerves by blocking the harmful effects on nerve health. They focused on a common condition known as chemotherapy-induced neuropathic pain (CINP), which causes tingling and pain to touch and cold temperatures, that can be severe enough to cause…

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Drug for Kidney Disease Tied to Infection Risk

Drug for Kidney Disease Tied to Infection Risk

A clinical trial was stopped early when researchers discovered that patients on the drug — a corticosteroid called methylprednisolone — suffered a concerning number of serious side effects. Most often, that meant severe infections, including pneumonia and meningitis. Overall, nearly 15 percent of patients on the drug had a serious “adverse event” over two years, the investigators found. That compared with 3 percent of patients given placebo pills, the researchers reported. The study focused on patients with a form of kidney disease called immunoglobulin A (IgA) nephropathy. It arises when…

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Brazil issues first license for sale of a cannabis-based drug

Brazil issues first license for sale of a cannabis-based drug

Brazilian healthcare regulator Anvisa on Monday said it had issued the country’s first license for sale of a cannabis-based drug in the country after years of legal wrangling with patients. The multiple sclerosistreatment, an oral spray derived from marijuana and developed by Britain’s GW Pharmaceuticals PLC, is known as Sativex internationally and will be sold in Brazil under the brand name Mevatyl. The legal status of cannabis-based drugs has been a thorny issue in Brazil for years, with several patients fighting in the courts to circumvent prohibition. Anvisa has loosened…

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New drug shows promise in repairing failing hearts

New drug shows promise in repairing failing hearts

New drug shows promise in repairing failing hearts A new experimental drug has shown promise in restoring cardiac function after heart failure, according to results of an early human trial. The researchers found that an infusion of the drug cimaglermin was generally tolerated except for transient nausea and headache. “These findings support continued clinical development of the investigational drug cimaglermin, including further safety evaluations and detailing the potential improvement on clinical heart failure outcome measures,” said lead author of the study Daniel Lenihan from Vanderbilt University in Nashville, Tennessee, US….

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