Rare Skin Reactions after mRNA Vaccination, Similar to Jones–Mote Basophil Responses

In a small group of recipients of messenger RNA (mRNA) vaccines against coronavirus disease 2019 (Covid-19), the occurrence of erythematous and indurated skin reactions has been reported at an average of 8 days after the first or second injection.1 The identification of such hypersensitivity responses has been a focus of study for many years by researchers investigating various systems. Such reactions to mRNA vaccines strongly resemble the primary first-dose flare and secondary skin-test responses that we reported 45 years ago in volunteers who were injected with foreign proteins2 (Figure 1A). At that…

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Parents, here are some effective techniques to ease your child’s vaccination pain

The pain of jabs can sometimes be a barrier to getting kids vaccinated, but according to a recent study, the pokes don’t have to be so petrifying, and parents can actually play a big role in soothing the sting. The research from York University’s OUCH Cohort at the Faculty of Health found that the amount of distress and pain felt by a preschooler during a vaccination is strongly related to how their parents help them cope before and during an appointment. In the study, researchers used the data from 548…

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